Scientific Research

The latest academic research on THR and its life-saving benefits

A vital component of THR is to prevent disease and save lives by providing access to accurate information about the lower risks of reduced harm products relative to cigarette smoking.

Nicotine vs. Smoking

Risk continuum shows nicotine products can save lives at a faster rate than previously possible.

Annual Review of Public Health

Nicotine is relatively harmless, all the harm from smoking comes from tobacco smoke.

Public Health England

Nicotine products significantly reduce harm and the risk of tobacco-related disease.


Vaping and nicotine pouches are 99.75% less risky than cigarettes

OSF Preprints


E-cigarettes help smokers to stop smoking in the long term.

Cochrane Library

Vaping is twice as effective as NRT.

New England Journal of Medicine

E-cigarettes help smokers get off and stay off cigarettes long term.

Addictive Behaviours Journal

There is a direct link between the declining smoking rates in the US and e-cigarette uptake.

British Medical Journal

90% of smokers start vaping to help them quit

European Tobacco Harm Reduction Advocates (ETHRA)

Vapers 5x more likely to quit than those who go cold turkey


Saving Lives

Vaping helps 50,000 – 70,000 smokers quit every year in the UK.


700,000 smokers have quit thanks to vaping in France.

European Journal of Public Health

Nicotine pouch use has helped Sweden achieve the lowest smoking rate in Europe.

Royal College of Physicians

15 past presidents of the Society for Research on Nicotine and Tobacco say vaping can benefit public health

American Journal of Public Health

6.6 million lives could be saved in the US over the next ten years by switching Smokers to vaping.

Georgetown University Medical Center

E-cigarettes could save 3.3 million life-years by 2070.

Nicotine & Tobacco Research

Tobacco Harm Reduction

A definitive resource for tobacco harm reduction research.

An advocates guide to tobacco harm reduction and campaigning for safer alternatives.

Saving Lives

Statements by international health organisations on the importance of tobacco harm reduction.

Various Authors

Alcohol Harm Reduction

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Alcohol Harm Reduction

Drug Harm Reduction

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Drug Harm Reduction